Managing chronic headaches can feel overwhelming, especially when standard treatments fall short. This is where innovative approaches, like Multiple Cranial Nerve Blocks (MCNB), may offer new hope for relief.

Headaches often involve pain in both the front (forehead) and back (neck) regions of the head, due to the connections between different nerves. The trigeminal nerve, which affects the face and forehead, and the occipital nerves, which affect the back of the head, play key roles in these headaches.

Multiple Cranial Nerve Blocks (MCNB) involve injecting medication to block the pain signals from several of these nerves, specifically targeting areas like the greater occipital nerve (GON), lesser occipital nerve (LON), and branches of the trigeminal nerve such as the supraorbital and supratrochlear nerves.

This is a different procedure than the typical nerve blocks targeting only the greater occipital nerve (GON).

illustration showing the nerves involved

This illustration from the paper discussed below shows the nerves that may be targeted. Source: Figure 1 in Miller et al. Cephalalgia. 2019

 

A recent study at London’s National Hospital for Neurology and Neurosurgery explored the benefits of MCNB in patients who suffer from chronic headaches, including chronic migraines, cluster headaches, and other rare headache conditions. These patients had typically tried other treatments, like GON blocks alone, but either saw little success or had diminishing benefits over time.

 

Key Findings from the Study

  • Positive Response: 55.4% of patients reported improvements after 2 weeks of MCNB treatment. For some, like those with cluster headaches, this improvement lasted for several weeks.
  • Specific Headache Conditions: The results varied depending on the type of headache. For instance, chronic migraine patients had a 49% response rate, while those with cluster headaches saw a 69.2% response. On the other hand, conditions like new daily persistent headache showed only a brief, 2-week improvement.
  • Lasting Effects: Over half of the patients who responded to the treatment saw their benefits last for up to 4 weeks. This suggests that MCNB may be a good option while waiting for long-term preventative treatments to take effect.
  • Safety: The side effects of MCNB were minimal, with common complaints being minor discomfort at the injection site, dizziness, or neck pain.

 

Why MCNB May Help Chronic Migraine Sufferers

For those experiencing frequent migraines that don’t respond well to conventional treatments, MCNB offers a promising alternative. This procedure can quickly provide relief and help reduce the number of migraine days, the intensity of attacks, and overall pain levels.

Moreover, this treatment may be repeated safely over time, allowing patients to avoid the side effects of oral steroids or intravenous medications.

Things to Keep in Mind

While MCNB appears to be effective for many patients, it’s not a cure. Some patients may experience more significant benefits than others, depending on their headache type. Additionally, although placebo effects could play a role, for those struggling with chronic headaches, any reduction in pain—whether from the treatment itself or a placebo effect—can improve quality of life.

If you’re dealing with chronic headaches or migraines, talking to a neurologist about MCNB may be a worthwhile conversation. It could offer you the chance to break free from the cycle of unrelenting headaches and find a treatment that provides both quick relief and sustained benefits, while you continue to work on addressing the root causes.